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Complement C3 and C4 Test
The complement system is an integral part of innate and
acquired immunity. There are 3 pathways- the classical, lectin and
alternative pathway. The complement component C3 is a key protein in all
reaction pathways, while the component C4 is part of the classical and lectin
pathway. Activation of the complement cascade can result in consumption of C3
and / or C4, and therefore a reduction in their concentration. We routinely
test complement C3 and C4 levels.
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Test:
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Functional Antibody Test
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Laboratory
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Immunology Laboratory |
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Specimen Type:
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Serum |
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Storage:
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If samples have to be stored prior to dispatch, please keep at 4°C |
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Posting Details:
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Room temperature |
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Posting Address:
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Department of Immunology, City Hospital, Dudley Road,
Birmingham, B18 7QH |
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Clinical Use:
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C3 /C4 levels are useful in monitoring conditions associated with
immune complexes e.g. SLE,systemic vasculitis |
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Turnaround:
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Approximately 24 hours |
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External QA Scheme:
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UK NEQAS, C1 inhibitor and functional complement |
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CPA Accredited Lab/Test:
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Full accreditation |
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Key Contact:
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Shabir Rajpar
Email:
info@cityassays.org.uk
Tel: 0121 507 4258 |
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Clinical Lead for this assay:
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Dr Sadia Noorani
Tel: 0121 507 5157 |
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